Treatment Information

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Non-Hodgkin's Lymphoma treatment details. Chemotherapy, Hormone, Biologic therapy.

Weill Cornell Medical College, New York, NY, United States.

Survival: monthsCountry:United States
Toxiciy Grade:4City/State/Province:New York, NY
Treatments:Chemotherapy, Hormone, Biologic therapyHospital:Weill Cornell Medical College
Drugs:Journal:Link
Date:Apr 2014

Description:

Patients:
This phase 2 study involved 11 mantle cell lymphoma patients who had not been previously treated. The median patient age was 60 years and 8 were men.

Treatment:
Patients were treated with the biologic therapy agent bevacizumab and a treatment regimen called R-CHOP that consists of rituximab (biologic) cyclophosphamide, adriamycin, vincristine (chemotherapy), and prednisone (hormone).

Toxicities:
The most severe toxicities were of grade 4 and included grade 3-4 anemia, neutropenia, and heart dysfunction.

Results:
The median overall survival was 48 months.

Support:
One of the authors has received funding from Genentech and Biogen Idec.

Correspondence: Dr. John P. Leonard; email: [email protected]



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