Treatment Information

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Melanoma treatment details. Immunotherapy.

Aarhus University Hospital, Aarhus, Denmark.

Survival: monthsCountry:Denmark
Toxiciy Grade:4City/State/Province:Aarhus
Treatments:ImmunotherapyHospital:Aarhus University Hospital
Drugs:Journal:Link
Date:Dec 2002

Description:

Patients: This Phase II study involved 41 patients with metastatic melanoma. The median age was 56.

Treatment: The treatment consisted of the drug histamine dihydrochloride and two immunotherapy agents: interleukin-2 and interferon-alpha.

Toxicity: Grade 3-4 toxicities included altered hearing, anemia, cardiovascular, diarrhea, infection, lethargy, nausea, pulmonary, and vomiting.

Results: The overal median survival was 7.8 months.

Support: The study was supported by grants from Maxim Pharmaceuticals, Chiron, and Schering Plough. Maxim manufactures or markets histamine dihydrochloride. Chiron markets or manufactures interleukin-2. Schering markets or manufactures interferon-alpha2B.

Correspondence: H. Schmidt, MD




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