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Liver Cancer treatment details. Biologic therapy.

Istituto Clinico Humanitas, Rozzano, Italy.

Survival: monthsCountry:Italy
Toxiciy Grade:4City/State/Province:Rozzano
Treatments:Biologic therapyHospital:Istituto Clinico Humanitas
Drugs:Journal:Link
Date:Sep 2010

Description:

Patients:
This study involved 27 patients with advanced hepatocellular carcinoma. The median age of the group was 67 years and 82% were male.

Treatment:
Patients in this study were administered the biologic therapy NGR-hTNF, which has antivascular activity (limits blood supply to tumors).

Toxicities:
The highest toxicity grade reported in this study was grade 4 and included anemia, liver failure, and pulmonary embolism. The most common adverse events of any grade were chills (63%), pain (33%), and weakness (30%).

Results:
The reported median overall survival was 8.9 months.

Correspondence: Dr. Claudio Bordignon; email: [email protected]



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