Treatment Information

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Lung Cancer treatment details. Chemotherapy.

S. Luigi Hospital, Torino, Italy.

Survival: monthsCountry:Italy
Toxiciy Grade:5City/State/Province:Torino
Treatments:ChemotherapyHospital:S. Luigi Hospital
Drugs:Journal:Link
Date:Jul 2008

Description:

Patients:
This study involved patients with advanced non-small cell lung cancer (NSCLC). Patients were divided into two separate treatment groups. Group A consisted of 862 patients with a median age of 61.1 years and 70% male. Group B had 863 patients with a median age of 61.0 years and 70.1% were male.

Treatment:
Group A was treated with the chemotherapy agents cisplatin and pemetrexed. Group B was treated with the chemotherapy agents cisplatin and gemcitabine.

Toxicities:
Treatment-related deaths were reported for both treatment groups, 9 in group A and 6 in group B. Specific causes of death were not given. Other toxicities reported for group A included grade 3-4 neutropenia (15.1% of patients) and alopecia (11.9%). Patients in group B also reported grade 3-4 neutropenia (26.7%), alopecia (21.4%), and thrombocytopenia (12.7%).

Results:
The reported median overall survival for both group A and group B was 10.3 months.

Support:
This study was supported by Eli Lilly, the makers of pemetrexed and gemcitabine.

Correspondence: Dr. Giorgio Vittorio Scagliotti; email: [email protected]



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